Motif ID: STAT5{A,B}.p2

Z-value: 1.672


Transcription factors associated with STAT5{A,B}.p2:

Gene SymbolEntrez IDGene Name
STAT5A 6776 signal transducer and activator of transcription 5A
STAT5B 6777 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT5Achr17_+_37693090-0.457.8e-02Click!
STAT5Bchr17_-_37681917-0.058.5e-01Click!


Activity profile for motif STAT5{A,B}.p2.

activity profile for motif STAT5{A,B}.p2


Sorted Z-values histogram for motif STAT5{A,B}.p2

Sorted Z-values for motif STAT5{A,B}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT5{A,B}.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_49552638 1.634 NM_001083335
NM_013380
 ZFP112

zinc finger protein 112 homolog (mouse)

chr19_+_49248003 1.539 NM_013361
 ZNF223
zinc finger protein 223
chr19_+_39860398 1.456 NM_001012320
NM_018443
 ZNF302

zinc finger protein 302

chr6_-_27548438 1.389 NM_007149
 ZNF184
zinc finger protein 184
chr19_-_49309102 1.358 LOC100379224
hypothetical LOC100379224
chr19_+_42099073 1.317 NM_198539
 ZNF568
zinc finger protein 568
chr19_+_49290319 1.291 NM_013398
 ZNF224
zinc finger protein 224
chr19_+_49180171 1.273 NM_003445
NM_198089
 ZNF155

zinc finger protein 155

chr10_-_121345968 1.204 TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr19_+_49361054 1.184 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
 ZNF226




zinc finger protein 226




chr19_+_42033106 1.149 NM_003419
 ZNF345
zinc finger protein 345
chr19_-_42098758 1.144 NM_001171979
 ZNF829
zinc finger protein 829
chr10_-_98315090 1.142 TM9SF3
transmembrane 9 superfamily member 3
chr19_+_42400908 1.135 ZNF383
zinc finger protein 383
chr19_-_49131250 1.125 NM_003425
 ZNF45
zinc finger protein 45
chr19_+_49198916 1.102 NM_006300
 ZNF230
zinc finger protein 230
chr5_+_178219519 1.081 NM_058230
 ZNF354B
zinc finger protein 354B
chr1_-_219977424 1.079 NM_144728
 DUSP10
dual specificity phosphatase 10
chr19_+_49309350 1.078 NM_013362
 ZNF225
zinc finger protein 225
chr19_-_62781883 1.036 NM_017879
 ZNF416
zinc finger protein 416
chr19_+_62972861 1.008 ZNF586
zinc finger protein 586
chr19_-_62680703 1.005 NM_001024596
NM_001144068
 ZNF772

zinc finger protein 772

chr19_+_49221333 0.998 NM_001129996
NM_013360
 ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr19_+_62949972 0.959 NM_173632
 ZNF776
zinc finger protein 776
chr19_-_62782066 0.946 ZNF416
zinc finger protein 416
chr17_+_15543771 0.946 ZNF286A
zinc finger protein 286A
chr19_+_45194782 0.931 NM_178544
 ZNF546
zinc finger protein 546
chr12_-_44670475 0.929 SCAF11
SR-related CTD-associated factor 11
chr19_+_49408523 0.928 NM_182490
 ZNF227
zinc finger protein 227
chr17_-_18526296 0.920 NM_001145045
 ZNF286B
zinc finger protein 286B
chr19_+_49337548 0.907 NM_001144824
NM_006630
 ZNF234

zinc finger protein 234

chr19_+_62950001 0.891 ZNF776
zinc finger protein 776
chr11_+_65024889 0.889 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr19_-_41672598 0.883 ZNF566
zinc finger protein 566
chr18_-_45241014 0.856 NM_017653
 DYM
dymeclin
chr19_+_49337568 0.848 ZNF234
zinc finger protein 234
chr9_-_103200697 0.839 NM_019051
 MRPL50
mitochondrial ribosomal protein L50
chr19_+_42033564 0.831 ZNF345
zinc finger protein 345
chr3_+_171422908 0.809 NM_002740
 PRKCI
protein kinase C, iota
chr1_+_40769877 0.802 ZNF684
zinc finger protein 684
chr19_-_41672176 0.763 NM_032838
NM_001145343
NM_001145344
NM_001145345
 ZNF566



zinc finger protein 566



chr19_+_49023283 0.763 NM_181845
 ZNF283
zinc finger protein 283
chr19_+_62972808 0.728 NM_017652
 ZNF586
zinc finger protein 586
chr19_-_49500966 0.726 NM_004234
 ZNF235
zinc finger protein 235
chr19_-_62912347 0.717 NM_001085384
 ZNF154
zinc finger protein 154
chr19_+_39916935 0.692 ZNF181
zinc finger protein 181
chr14_-_67232172 0.691 NM_016026
 RDH11
retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr12_-_47250069 0.681 NM_002289
 LALBA
lactalbumin, alpha-
chr12_+_132167551 0.681 ZNF140
zinc finger protein 140
chr3_-_52839727 0.678 NM_001166449
NM_002218
 ITIH4

inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)

chr6_+_139136349 0.663 NM_015439
 CCDC28A
coiled-coil domain containing 28A
chr19_-_49696322 0.660 NM_013256
 ZNF180
zinc finger protein 180
chr19_-_61596681 0.660 NM_144690
 ZNF582
zinc finger protein 582
chr19_+_61798434 0.639 NM_021216
 ZNF71
zinc finger protein 71
chr5_-_178090203 0.638 NM_005649
 ZNF354A
zinc finger protein 354A
chr16_+_52295545 0.635 FTO
fat mass and obesity associated
chr9_+_103200939 0.626 NM_003452
NM_197977
 ZNF189

zinc finger protein 189

chr8_-_66708948 0.625 ARMC1
armadillo repeat containing 1
chr7_-_93471463 0.622 NM_005868
 BET1
blocked early in transport 1 homolog (S. cerevisiae)
chr1_-_33275015 0.611 AK2
adenylate kinase 2
chr5_+_32621361 0.609 NM_006713
 SUB1
SUB1 homolog (S. cerevisiae)
chr12_+_132167512 0.609 ZNF140
zinc finger protein 140
chr9_-_98656206 0.607 NM_001001662
 ZNF782
zinc finger protein 782
chr3_-_185218311 0.601 NM_001023587
NM_005688
 ABCC5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

chr19_+_39916964 0.599 ZNF181
zinc finger protein 181
chr16_-_52295214 0.595 NM_001127897
NM_015272
 RPGRIP1L

RPGRIP1-like

chr19_+_62638474 0.594 NM_001023561
 ZNF749
zinc finger protein 749
chr20_-_18425811 0.589 NM_006606
 RBBP9
retinoblastoma binding protein 9
chr19_+_49147219 0.567 NM_013359
 ZNF221
zinc finger protein 221
chr19_+_62836322 0.566 NM_006385
NM_198855
 ZNF211

zinc finger protein 211

chr7_+_89870707 0.563 CLDN12
claudin 12
chr6_-_83960351 0.562 PGM3
phosphoglucomutase 3
chr11_-_125278296 0.552 NM_031307
 PUS3
pseudouridylate synthase 3
chr2_+_161873031 0.551 NM_005805
 PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr5_+_178383381 0.549 NM_001136116
 ZNF879
zinc finger protein 879
chr8_-_56848423 0.547 NM_152417
 TMEM68
transmembrane protein 68
chr9_+_129226473 0.538 NM_007135
 ZNF79
zinc finger protein 79
chr19_-_41849558 0.534 NM_153257
 ZNF461
zinc finger protein 461
chr9_-_133944877 0.531 MED27
mediator complex subunit 27
chr16_-_219111 0.531


chr19_-_41711009 0.526 NM_001012756
NM_001166036
NM_001166037
NM_001166038
 ZNF260



zinc finger protein 260



chr10_+_124903874 0.525 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr7_+_89870647 0.523 NM_001185072
NM_001185073
NM_012129
 CLDN12


claudin 12


chr17_-_5263594 0.523 NUP88
nucleoporin 88kDa
chr19_+_63053031 0.519 NM_032828
 ZNF587
zinc finger protein 587
chr18_-_41938196 0.510 NM_001001937
 ATP5A1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
chr1_+_40769819 0.504 NM_152373
 ZNF684
zinc finger protein 684
chr8_-_66708967 0.500 NM_018120
 ARMC1
armadillo repeat containing 1
chr11_-_82675024 0.498 NM_021825
 CCDC90B
coiled-coil domain containing 90B
chr9_-_103185621 0.498 NM_001127610
 BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr12_-_44670632 0.493 NM_004719
 SCAF11
SR-related CTD-associated factor 11
chr19_+_49455872 0.492 NM_181756
 ZNF233
zinc finger protein 233
chr1_-_33275071 0.489 NM_013411
 AK2
adenylate kinase 2
chr17_+_15543615 0.482 NM_001130842
NM_020652
 ZNF286A

zinc finger protein 286A

chr7_+_98940537 0.480 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr1_+_151897768 0.480 NM_012437
 SNAPIN
SNAP-associated protein
chr2_+_95194903 0.478 NM_001017396
NM_021088
 ZNF2

zinc finger protein 2

chr19_-_42098919 0.466 NM_001037232
 ZNF829
zinc finger protein 829
chr3_+_66094324 0.463 NM_173471
 SLC25A26
solute carrier family 25, member 26
chr17_+_5264195 0.462 RPAIN
RPA interacting protein
chr19_-_63018092 0.460 NM_024762
 ZNF552
zinc finger protein 552
chr1_+_38250953 0.459 NM_016037
 UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr1_+_38250995 0.458 UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr8_-_109330116 0.451 NM_001568
 EIF3E
eukaryotic translation initiation factor 3, subunit E
chr15_+_20384835 0.450 NM_001102610
NM_052903
 TUBGCP5

tubulin, gamma complex associated protein 5

chr11_-_133628348 0.447 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
 THYN1




thymocyte nuclear protein 1




chr12_+_132167057 0.445 NM_003440
 ZNF140
zinc finger protein 140
chr2_+_95195260 0.439 ZNF2
zinc finger protein 2
chr18_+_41938295 0.439 NM_138443
 HAUS1
HAUS augmin-like complex, subunit 1
chr19_-_42777486 0.433 NM_016536
 ZNF571
zinc finger protein 571
chr3_+_140545528 0.420 NM_020191
 MRPS22
mitochondrial ribosomal protein S22
chr2_+_43854681 0.418 NM_001193464
NM_015522
NM_016008
 DYNC2LI1


dynein, cytoplasmic 2, light intermediate chain 1


chr8_-_109330101 0.418 EIF3E
eukaryotic translation initiation factor 3, subunit E
chr5_+_150008030 0.417 SYNPO
synaptopodin
chr19_+_63611819 0.413 NM_173548
 ZNF584
zinc finger protein 584
chr19_+_63611930 0.410 ZNF584
zinc finger protein 584
chr14_-_81069865 0.407 SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr3_+_132228383 0.407 NM_001146003
NM_024800
NM_145910
 NEK11


NIMA (never in mitosis gene a)- related kinase 11


chr1_-_54291378 0.404 TMEM59
transmembrane protein 59
chr9_-_133945064 0.402 NM_004269
 CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr19_-_63205948 0.398 ZNF606
zinc finger protein 606
chr5_-_145542407 0.396 LARS
leucyl-tRNA synthetase
chr14_+_96333434 0.395 NM_003384
 VRK1
vaccinia related kinase 1
chr7_+_98940508 0.393 NM_014569
 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr8_-_101384633 0.392 NM_015435
 RNF19A
ring finger protein 19A
chr3_-_158695832 0.392 NM_001167917
 VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr2_+_88772281 0.378 NM_144563
 RPIA
ribose 5-phosphate isomerase A
chr22_-_37232261 0.377 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr11_-_82674546 0.375 CCDC90B
coiled-coil domain containing 90B
chr22_-_37232290 0.373 NM_001098504
NM_006386
 DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr2_+_171999042 0.367 DCAF17
DDB1 and CUL4 associated factor 17
chr1_+_40715465 0.365 ZNF642
zinc finger protein 642
chr2_-_84540096 0.365 NM_003849
 SUCLG1
succinate-CoA ligase, alpha subunit
chr19_+_50601708 0.364 CD3EAP
CD3e molecule, epsilon associated protein
chr4_+_174528602 0.358 NM_003864
 SAP30
Sin3A-associated protein, 30kDa
chr12_-_44670613 0.356 SCAF11
SR-related CTD-associated factor 11
chr3_+_197951121 0.356 NM_002577
 PAK2
p21 protein (Cdc42/Rac)-activated kinase 2
chr5_-_111120817 0.356 NM_004772
 C5orf13
chromosome 5 open reading frame 13
chr19_+_9112052 0.354 NM_001190791
NM_020933
 ZNF317

zinc finger protein 317

chr2_+_63669596 0.343 NM_005917
 MDH1
malate dehydrogenase 1, NAD (soluble)
chr20_+_35266581 0.341 RPN2
ribophorin II
chr20_-_25625173 0.336 NM_015655
 ZNF337
zinc finger protein 337
chr7_-_112545840 0.335 LOC401397
hypothetical LOC401397
chr14_-_19951417 0.334 NM_007110
 TEP1
telomerase-associated protein 1
chrX_+_105932536 0.328 NM_017752
NM_198881
 TBC1D8B

TBC1 domain family, member 8B (with GRAM domain)

chr12_+_12857516 0.328 NM_016355
NM_201224
 DDX47

DEAD (Asp-Glu-Ala-Asp) box polypeptide 47

chr13_-_24395054 0.321 NM_018451
 CENPJ
centromere protein J
chr9_+_15412875 0.318 SNAPC3
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr9_-_114814286 0.316 NM_001101338
 ZNF883
zinc finger protein 883
chr3_-_120861959 0.315 NM_022135
 POPDC2
popeye domain containing 2
chr15_-_72540518 0.315 UBL7
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr1_-_233734403 0.313 NM_152490
 B3GALNT2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr14_+_22305570 0.310 NM_005015
 OXA1L
oxidase (cytochrome c) assembly 1-like
chr9_+_129226535 0.310 ZNF79
zinc finger protein 79
chr6_-_159160355 0.308 EZR
ezrin
chr14_-_81069951 0.306 NM_005065
 SEL1L
sel-1 suppressor of lin-12-like (C. elegans)
chr6_+_88239423 0.305 SLC35A1
solute carrier family 35 (CMP-sialic acid transporter), member A1
chr19_+_58733144 0.305 NM_001079906
 ZNF331
zinc finger protein 331
chr22_-_37232246 0.304 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr13_+_24844084 0.302 NM_016529
 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr15_-_81744469 0.299 NM_001717
 BNC1
basonuclin 1
chr1_+_53165545 0.293 SCP2
sterol carrier protein 2
chr15_-_81527109 0.292 NM_001011885
NM_025238
 BTBD1

BTB (POZ) domain containing 1

chr14_+_23700261 0.291 NM_006084
 IRF9
interferon regulatory factor 9
chr6_-_159160421 0.290 NM_001111077
 EZR
ezrin
chr8_+_124154117 0.287 WDR67
WD repeat domain 67
chr3_-_132228273 0.287 NM_014065
 ASTE1
asteroid homolog 1 (Drosophila)
chr6_+_84626113 0.282 CYB5R4
cytochrome b5 reductase 4
chr15_-_81526896 0.281 BTBD1
BTB (POZ) domain containing 1
chr4_+_174528675 0.279 SAP30
Sin3A-associated protein, 30kDa
chr7_+_98940208 0.278 NM_145102
 ZKSCAN5
zinc finger with KRAB and SCAN domains 5
chr5_+_178300799 0.277 NM_001178089
NM_001178090
NM_182594
 ZNF454


zinc finger protein 454


chr8_-_66708954 0.275 ARMC1
armadillo repeat containing 1
chr3_+_123882355 0.274 NM_017554
 PARP14
poly (ADP-ribose) polymerase family, member 14
chr19_+_55221088 0.273 ZNF473
zinc finger protein 473
chr4_+_2853434 0.270 ADD1
adducin 1 (alpha)
chr20_-_42713663 0.269 ADA
adenosine deaminase
chr5_-_95184121 0.264 GLRX
glutaredoxin (thioltransferase)
chr6_+_84626083 0.263 NM_016230
 CYB5R4
cytochrome b5 reductase 4
chr19_-_41955493 0.262 NM_001193552
 ZNF850
zinc finger protein 850
chr19_+_55221106 0.262 ZNF473
zinc finger protein 473
chr1_-_233734088 0.255 B3GALNT2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr4_+_70831387 0.252 NM_001025104
NM_001890
 CSN1S1

casein alpha s1

chrX_+_149487677 0.251 NM_000252
 MTM1
myotubularin 1
chr16_+_52025891 0.250 RBL2
retinoblastoma-like 2 (p130)
chr5_-_145542261 0.248 LARS
leucyl-tRNA synthetase
chr1_-_233734311 0.248 B3GALNT2
beta-1,3-N-acetylgalactosaminyltransferase 2
chr6_+_20642665 0.246 NM_017774
 CDKAL1
CDK5 regulatory subunit associated protein 1-like 1
chr5_-_145542428 0.243 NM_020117
 LARS
leucyl-tRNA synthetase
chr7_-_132417374 0.241 CHCHD3
coiled-coil-helix-coiled-coil-helix domain containing 3
chr1_-_206125877 0.240


chr10_+_43421889 0.238 ZNF485
zinc finger protein 485
chr19_+_49268106 0.237 NM_001037813
 ZNF284
zinc finger protein 284
chr1_-_33275057 0.236 NM_001625
 AK2
adenylate kinase 2
chr7_-_133652289 0.235 NM_032826
 SLC35B4
solute carrier family 35, member B4
chr19_+_63022879 0.235 LOC100293516
zinc finger protein
chr14_-_69953433 0.234 NM_018373
 SYNJ2BP
synaptojanin 2 binding protein
chr21_-_35174742 0.231 RUNX1
runt-related transcription factor 1
chr6_-_159160386 0.231 EZR
ezrin
chr8_+_124154079 0.231 NM_001145088
NM_145647
 WDR67

WD repeat domain 67


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.27 3.64e-11 GO:0006355 regulation of transcription, DNA-dependent
2.13 3.27e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.18 3.42e-10 GO:0051252 regulation of RNA metabolic process
2.10 6.06e-10 GO:0010556 regulation of macromolecule biosynthetic process
2.04 3.60e-09 GO:0010468 regulation of gene expression
1.97 7.28e-09 GO:0051171 regulation of nitrogen compound metabolic process
1.97 1.42e-08 GO:0009889 regulation of biosynthetic process
1.97 1.79e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97 1.79e-08 GO:0031326 regulation of cellular biosynthetic process
1.80 1.22e-07 GO:0060255 regulation of macromolecule metabolic process
1.73 6.94e-07 GO:0031323 regulation of cellular metabolic process
1.72 1.36e-06 GO:0080090 regulation of primary metabolic process
1.65 3.47e-06 GO:0019222 regulation of metabolic process
1.33 3.42e-03 GO:0050794 regulation of cellular process
1.29 4.95e-03 GO:0065007 biological regulation
1.28 2.61e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.41 8.02e-16 GO:0043229 intracellular organelle
1.41 1.08e-15 GO:0043226 organelle
1.45 8.04e-15 GO:0043231 intracellular membrane-bounded organelle
1.45 9.51e-15 GO:0043227 membrane-bounded organelle
1.67 4.55e-13 GO:0005634 nucleus
1.29 6.52e-12 GO:0044424 intracellular part
1.27 9.43e-11 GO:0005622 intracellular
1.09 9.72e-03 GO:0044464 cell part
1.09 9.84e-03 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.52 2.94e-16 GO:0008270 zinc ion binding
2.39 3.31e-16 GO:0046914 transition metal ion binding
2.30 2.54e-14 GO:0003677 DNA binding
1.89 9.59e-11 GO:0003676 nucleic acid binding
1.77 3.74e-10 GO:0046872 metal ion binding
1.75 8.65e-10 GO:0043169 cation binding
1.74 1.04e-09 GO:0043167 ion binding